Tetrabromobisphenol A(TBBPA) is the most widely used BFR (brominated flame retardants) as a reactive flame retardant in printed circuit boards, and as additive applications in several types of polymers. The purpose of this study is to assess the adverse effects of TBBPA on the benthic amphipod (Hyalella azteca). Results on the acute toxicity of TBBPA using Hyalella azteca showed that NOEC and LOEC are 100 ㎎/㎏ and 200 ㎎/㎏, respectively. In addition, when chronic toxicity of TBBPA was investigated at the concentration ranges between 0.01 to 100 ㎎/㎏, it was found that NOECs are 10 ㎎/㎏ (fecundity)~100 ㎎/㎏ (viability), respectively. Significant fecundity inhibition was appeared at 100 ㎎/㎏ of TBBPA, however, this concentration did not show severe adverse effect on weight increment. The values of PNEC were determined as 0.1 ㎎/㎏(fecundity) and 1 ㎎/㎏ (lethal effect), respectively, using a safety factor suggested by EU and OECD.
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