Relationship between residential district and health-related quality of life in Chungnam industrial complex area

Article information

Environ Health Toxicol. 2016;31.e2016017
Publication date (electronic) : 2016 August 26
doi : https://doi.org/10.5620/eht.e2016017
1Department of Occupational and Environmental Medicine, Dankook University College of Medicine, Cheonan, Korea
2Center for Farmers’ Safety and Health, Dankook University Hospital, Cheonan, Korea
Correspondence: Sangchul Roh, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Korea Tel: +82-41-550-3956 Fax: +82-41-556-6461 E-mail: scroh@dku.edu
Received 2016 July 27; Accepted 2016 August 5.

Abstract

Objectives

This study aimed to evaluate the relationship between residential district of people, such as power plant, steel-mill and petrochemical industries, and health-related quality of life (HRQoL).

Methods

Using a cross-sectional study design, we randomly recruited participants for our study from industrial areas (thermoelectric power plant, steel-mill, petrochemical industry) and rural areas. Logistic regression analysis was used to identify the relationships between Euro quality of life-5 dimension (EQ-5D) scores and living region, while controlling for sociodemographic characteristics.

Results

In adjusted model, quality of life decreased with increasing category of age and were lower for females than males. EQ-5D scores of people living in the vicinity of thermoelectric power plant were significant lower than those of people living the vicinity of comparison region (odds ratio, 1.59; 95% confidence interval, 1.00 to 2.53).

Conclusions

Living region of thermoelectric power plant, was strongly associated with scores on the EQ-5D. More research is needed to elucidate the mechanisms which makes the relationship with the living regions and HRQoL.

Introduction

Since 1962, South Korea (hereafter Korea) has achieved rapid growth due to the implementation of a what started as a 5-year economic development plan. During the early years of economic development, Korea chiefly strived to expand energy sources, such as electricity and coal, and national infrastructure, such as roads, ports, railroads, telecommunications, electric power, and water supply. In the 1970’s, the nation focused on industrialization of the heavy chemical industry. Energy, steel, and petrochemical products played important roles in this industrialization process [1]. In particular, many national and public industrial complexes were built in the Chungnam region because of its geographic proximity to the capitol area and the west coast, which allowed easy access to ports, seawater, and smooth trade with China [2].

While such industrialization achieved economic development, it polluted the air, soil, and water quality of the regions in which industrial facilities continuously released exhaust and wastewater. In the process of combusting fossil fuels and refining metal, heavy metal was created, which then polluted the surrounding areas by either falling to the ground after becoming absorbed into the dust emitted from the combustion process, or by rain. Because these sources of pollution can become absorbed into the body and breed both acute and chronic health hazards, the stench from industrial complexes could cause a great deal of mental and psychological damage to its neighboring residents [1,3].

Investigation of the health effects from the surrounding areas of industrial complexes were mainly carried out by an official checking the magnitude of pollutant emission, assessing the amount of pollutants accumulated in the body, and diagnosing diseases based on a medical examination [2]. However, it is difficult for investigations on health to reflect the effects of industrial complexes on the quality of life (QoL) of neighboring residents. This is because the concept of health is gradually evolving toward valuing the QoL, not just extending it [4].

Euro quality of life-5 dimension (EQ-5D) is a health-related quality of life (HRQoL) index that has been internationally standardized. The need to consider the multi-dimensionality of health makes health evaluation challenging. In other words, we need to comprehensively consider aspects such as physical, functional, subjective, and mental health. EQ-5D is measured based on a respondent’s self-evaluation of experiences such as motor ability, self-care, usual activities, pain/discomfort, and anxiety/depression. While EQ-5D is a subjective index because of its self-evaluation method, it is also a comprehensive measurement index that takes into account the multi-dimensionality of health, since it encompasses the physical, functional, and mental dimensions [5].

The objective of this study is to evaluate the QoL of residential districts around the power plant, steel mill, and petrochemical industrial complexes built in Chungnam. First, we will compare the QoL between residential districts in industrial areas and residents living in areas that are considered to be unaffected by industrial complexes. Second, we will analyze the factors that affect the QoL within near an industrial complex. In particular, we will investigate the relevance between the distance from a facility to the QoL.

Materials and Methods

Study Subjects

Six regions were randomly selected from areas vulnerable to environmental pollution: four regions bordering the Chungnam power plant, steel mill, and petrochemical industrial complexes (Dangjin Power Plant, Boryeong Power Plant, Seocheon Power Plant, Taean Power Plant), the Dangjin Steel Mill, and Seosan Petrochemical Industrial Complex. Moreover, four comparison regions were selected that are located at least 30 km from an industrial complex and have low exposure to environmental pollution: Cheongyang and Gongju were selected as inland comparison regions while Hongseong and Taean (located near the seashore) were selected as coastal comparison regions. Then, administrative districts at the village level were selected within the regions of each city and province and surveys of the residents were conducted.

The surveys were carried out from November 2013 to December 2015. The subjects of the study were limited to adult residents of the selected regions who were age 20 or older, and the surveys were conducted on local medical check-up examinees. People who had previously been employed at an industrial complex, had suffered from a mental disorder, or had verbal communication issues were excluded. Out of the 1320 total subjects recruited, 1244 participated in the surveys.

Based on the 2013 resident registration population, 385410 residents over the age of 20 lived in the power plant industrial complex region, 159615 in the steel mill industrial complex region, 165837 in the petrochemical industrial complex region, and 300644 in the comparison regions. Since villages were randomly selected within the industrial areas and the comparison regions and then surveys of the village residents were conducted, the survey results represent each region.

The research ethics committee of Dankook University Hospital approved this study (DKUH 2013-10-005), and before conducting the surveys, consent was received from all research subjects.

Questionnaire

In addition to 36-Item Short Form Health Survey Instrument (SF-36), EQ-5D is one of the most widely used QoL evaluation instrument in the clinical research field. EQ-5D has been translated into more than 130 languages worldwide and is used in a variety of fields. EQ-5D is a general health measurement instrument that not only describes a patient’s QoL, but can also present a single summary index by applying weights to each of the levels in each dimension. These weights are calculated based on the valuation of health states from general population samples. EQ-5D is composed of five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Each dimension is divided into three levels: no problems, some problems, and extreme problems. EQ-5D is simple and does not take a long time to complete. The questionnaire can be self-completed or by face-to-face interviews.

Based on the above questions, EQ-5D calculates a score by attaching different weights to each question. A unique valuation is calculated and used after taking into account each country’s conditions. Nam et al. [6] conducted a study that computed an EQ-5D valuation in Korea. This study adopted the valuation method used by Nam et al [6] since it is the official method used by the Korea National Health and Nutrition Examination Survey.

According to Nam et al. [6], an EQ-5D score is calculated by the following formula:

(1) Y=1-(0.050+0.096*M2+0.418*M3+0.046*SC2+0.136*SC3+0.051*UA2+0.208*UA3+0.037*PD2+0.151*PD3+0.043*AD2+0.158*AD3+0.050*N3)
  • M = mobility

  • SC = self-care

  • UA = usual activity

  • PD = pain/discomfort

  • AD = anxiety/depression

If a respondent selects level 1 for all of the dimensions, their EQ-5D score is one, and is deemed a healthy person by measurement standards. Based on this standard, if a respondent selects level 2 or 3 for the dimensions, we can calculate the EQ-5D score by subtracting the valuation presented in Formula (1). Therefore, the number of health states that can be described by EQ-5D is 35= 243, with a maximum distribution of one and a minimum of -0.171.

The constant 0.050 is subtracted in cases where even one of the five dimensions is in the category of level 2 or more. N3 is subtracted when a respondent answers with a level 3 (the worst health state) for even one of the questions. This is called a dysfunction dimension, and since this additional dimension is produced by the interactive characteristic of EQ-5D, it does not indicate an unhealthy state for one particular dimension, but for all five dimensions. There is a total of six dimensions in EQ-5D, including the dysfunction dimension. Because there is no fixed breaking point to define poor QoL, a breaking point was selected by the researchers randomly: the lower 10% fractile of the control group would represent poor QoL. Since many studies, including one by Jo and Lee [7], have verified the validity of EQ-5D, it was decided that this instrument could be used without further verification.

Confounder

Survey agents carried out research on subjects using EQ-5D and a questionnaire on socioeconomic standards. To determine socioeconomic status, respondents were asked about their sex, age, marital status, average monthly income, education level, employment status, and whether nor not they suffered from any chronic diseases.

Data Analysis

A frequency analysis was conducted on the demographic characteristics of the research subjects, as well as on the distribution of levels in each of the five dimensions of EQ-5D depending on the residential district. Finally, a logistics regression analysis was conducted on the declining QoL depending on socioeconomic status. Then the mean and standard deviation of the EQ-5D were calculated according to the distance from facilities in the industrial complex. After adjusting for the decline of QoL in residential districts according to socioeconomic levels, a regression analysis was conducted. SPSS version 23.0 (IBM Corp., Armonk, NY, USA) was used for all statistical analyses.

Results

The demographic characteristics of the subjects are summarized in Table 1. There was a higher portion of female residents living in areas vulnerable to environmental pollution, but there was a higher portion of male residents living in the comparison regions. There was a higher age range for power plant districts, with 42.0% of the population older than 70 years. The age range was lower for the petrochemical industrial complex, with 39.0% of the population younger than 59 years. More residents reported to be married in comparison regions (83.0%) than in areas vulnerable to environmental pollution. The greatest fraction of residents reported a 500000 Korean won or less monthly income, and the highest percentage of residents who fell into this category lived in power plant districts (45.6%). In terms of education level, the highest percentage of residents who had at least a top school diploma lived in the petrochemical industrial complex (40.9%) region. The employment rate was highest in comparison regions, at 76.3%, and lowest in steel mill districts, at 59.0%. The prevalence rate of chronic diseases was highest in power plant districts, at 49.0%.

Sociodemographic characteristics of study subjects

Table 2 summarizes the distribution of levels in each of the five dimensions of EQ-5D depending on the residential district. The most frequently cited health issue in all of the districts was “pain/discomfort”. The percentage of residents complaining of “mobility” issues was higher in power plant districts (47.7%) and steel mill districts (46.4%) than that of petrochemical industrial complex and comparison regions. The percentage of residents who complained of “self-care” issues was highest in power plant districts, at 13.8%, and lowest in comparison regions, at 7.8%. The percentage of residents complaining of “usual activities” issues was higher in power plant districts (26.8%) and steel mill districts (26.1%) than that of petrochemical industrial complex and comparison regions. The percentage of residents complaining of “pain/discomfort” was higher in power plant districts (66.5%) and comparison regions (63.8%) than that of steel mill districts and petrochemical industrial complex regions. The percentage of residents who complained of “anxiety/depression” issues was highest in power plant districts, at 31.4%, and lowest in the petrochemical industrial complex areas at, 19.5%.

Distribution of Euro quality of life-5 dimension (EQ-5D)a

The analysis of the results of socioeconomic factors that impact EQ-5D in residential districts is summarized in Table 3. In power plant districts, the degree of risk for a decline in QoL was significantly higher for females than males (odds ratio [OR], 2.76; 95% confidence interval [CI], 1.40 to 5.43) and residents in the over 70s age group than residents in the under 50s age group (OR, 4.91; 95% CI, 1.89 to 12.79). In steel mill districts, the degree of risk for a decline in QoL was significantly higher for females than males (OR, 10.99; 95% CI, 2.12 to 57.03). In petrochemical industrial complex areas, there was no significant difference between socioeconomic factors in the degree of risk for a decline in QoL.

Odds ratios and 95% confidence interval for impaired health-related quality of life

Table 4 presents the mean and standard deviation of EQ-5D according to the distance from facilities in the industrial complex area. For power plant and steel mill districts, there wasn’t a fixed tendency for the distance to impact the QoL. However, results for the petrochemical industrial complex region, showed that the closer the distance to the facilities, the higher the QoL.

Means and standard deviations of Euro quality of life-5 dimension according to the distance of industrial facilities

Table 5 presents the regression analysis results on the decline of QoL in residential districts according to socioeconomic levels. When compared to the results of the comparison regions, the degree of risk for a decline in QoL was higher in industrial areas both before and after adjusting for socioeconomic factors, but the number was not statistically significant. When we analyzed each industrial complex, however, the degree of risk for a decline in QoL was significantly higher in power plant districts than in comparison regions (OR, 1.78; 95% CI, 1.14 to 2.77). The degree of risk for a decline in QoL was statistically significant even when adjusted for sex, age, marital status, average monthly income, education level, employment status, and chronic diseases (OR, 1.59; 95% CI, 1.00 to 2.53). There was no significant difference in the QoL between power plant districts, petrochemical industrial complex areas, and comparison regions.

Odds ratios and 95% confidence intervals for impaired health-related quality of life according to living region

Discussion

Today, the quality aspect of health is getting as much attention as estimating the risk of disease outbreak. This is because health has become more than just about extending life—maintaining a healthy lifestyle has been highlighted over the years. The assessment of medical treatment is shifting from a third party perspective, in which a doctor describes symptoms, to a subjective perspective, in which a person evaluates his/her own health [8].

QoL can be classified into HRQoL and non-HRQoL. In the field of health and medical services, HRQoL is usually used. This category includes health levels based on personal experience, beliefs, and expectations, as well as the physical, mental, and social aspects of health according to cognitive abilities [5].

Compared to residents living in rural areas, those living around power plants and petrochemical industrial complexes are reported to have a higher outbreak of asthma, respiratory diseases, neurological disorders, and skin diseases. Residents living around the petrochemical industrial complex reported a higher rate of headaches, sneezing, and itchiness and irritation of the eyes than those living in rural areas. Residents living around power plants reported a higher rate of headaches, itchiness and irritation of the eyes, itchy skin, and sneezing than those living in rural areas. While there weren’t any instances of sleep disruption in rural areas due to the stench emitted from facilities in the industrial complexes, there was a high rate of sleep disruption in both the petrochemical industrial complex areas and the power plant districts. However, the numbers were not statistically significant [1,3]. The air in power plant districts exhibited a higher concentration of fine particulate matter (PM)–e.g., PM2.5, PM10 -and heavy metals– cadmium, chromium, arsenic, lead - than the air in other regions. These toxic substances have an effect on the outbreak of respiratory-related diseases such as asthma and cardiovascular diseases, which the elderly (over 60 years old) are especially susceptible to [1]. In addition, these substances can have a toxic effect on the gastrointestinal tract, kidneys, blood, and nerves.

The subjects of this study complained of “pain/discomfort” for many of the health- related questions. It is suspected that this was because the age of residents living in industrial districts and comparison regions were over age 60. When EQ-5D tests were conducted on senior citizens who visited health centers, the results also showed that they most frequently complained of “pain/discomfort” [9]. This could be because as people age, they become more sensitive to pain, and therefore complain of more pain related symptoms. In terms of socioeconomic factors, females reported a lower QoL than males, and the difference seems to result from Korea’s patriarchal culture [10,11]. The distance between industrial complexes did not contribute to a decline in QoL. The distance from the facilities was divided by 1 km and 3 km, which is believed to be too small to determine the effect of distance on QoL [12].

Because this study was carried out as a cross-sectional design study, it shows the correlation between residential districts and QoL, but does not have enough evidence to prove a causal relationship between the two. Moreover, this study cannot represent the whole population because it was only conducted in the Chungnam area. Finally, the selected subject pool was limited as well, since surveys were conducted only on medical check-up participants.

By measuring the QoL in industrial complex areas in Chungnam and in comparison areas, this study investigated the correlation between residential environment and subjective health. This study showed that the QoL declined for residents living around industrial complexes—especially those living around power plants. Therefore, additional assessments of factors that could negatively affect the HRQoL around power plants and policies to prevent them are needed.

Notes

The authors have no conflicts of interest associated with material presented in this paper.

References

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Article information Continued

Table 1.

Sociodemographic characteristics of study subjects

Thermoelectric power plant Steel mill Petrochemical industry Control p-valuea
Sex Male 223 (47.3) 125 (47.9) 64 (39.0) 185 (53.2) 0.03
Female 248 (52.7) 136 (52.1) 100 (61.0) 163 (46.8)
Age ≤59 139 (29.5) 80 (30.7) 64 (39.0) 114 (32.8) 0.009
60-69 134 (28.5) 90 (34.5) 44 (26.8) 127 (36.5)
≥70 198 (42.0) 91 (34.9) 56 (34.1) 107 (30.7)
Marital status Yes 367 (77.9) 208 (79.7) 128 (78.0) 289 (83.0) 0.31
Nob 104 (22.1) 53 (20.3) 36 (22.0) 59 (17.0)
Monthly income (104 Korean won) ≤49 214 (45.6) 113 (43.3) 74 (45.1) 147 (42.4) 0.80
50-199 175 (37.3) 95 (36.4) 55 (33.5) 129 (37.2)
≥200 80 (17.1) 53 (20.3) 35 (21.3) 71 (20.5)
Education Uneducated 106 (22.5) 51 (19.5) 38 (23.2) 64 (18.4) 0.32
Elementary 207 (43.9) 119 (45.6) 59 (36.0) 160 (46.0)
middle or higher 158 (33.5) 91 (34.9) 67 (40.9) 124 (35.6)
Employed status Yes 316 (67.1) 154 (59.0) 124 (76.1) 264 (76.3) <0.001
No 155 (32.9) 107 (41.0) 39 (23.9) 82 (23.7)
Chronic diseasec Yes 247 (47.6) 128 (49.0) 67 (40.9) 142 (40.9) 0.09
No 224 (52.4) 133 (51.0) 97 (59.1) 205 (59.1)

Values are presented as number (%).

a

p-values of chi-square test.

b

Unmarried/divorced/widowed.

c

Hypertension, diabetes mellitus, dyslipidemia, chronic obstructive pulmonary disease.

Table 2.

Distribution of Euro quality of life-5 dimension (EQ-5D)a

Level Thermoelectric power plant Steel mill Petrochemical industry Control p-valueb
Mobility 1 246 (52.2) 140 (53.6) 99 (60.4) 218 (62.6) 0.06
2 223 (47.3) 120 (46.0) 64 (39.0) 130 (37.4)
3 2 (0.4) 1 (0.4) 1 (0.6) 0 (0.0)
Self-care 1 406 (86.2) 229 (87.7) 146 (89.0) 321 (92.2) 0.05
2 64 (13.6) 29 (11.1) 17 (10.4) 27 (7.8)
3 1 (0.2) 3 (1.1) 1 (0.6) 0 (0.0)
Usual activity 1 345 (73.2) 193 (73.9) 125 (76.2) 283 (81.3) 0.06
2 120 (25.5) 67 (25.7) 39 (23.8) 64 (18.4)
3 6 (1.3) 1 (0.4) 0 (0.0) 1 (0.3)
Pain/discomfort 1 158 (33.5) 115 (44.1) 74 (45.1) 126 (36.2) 0.02
2 265 (56.3) 132 (50.6) 80 (48.8) 192 (55.2)
3 48 (10.2) 14 (5.4) 10 (6.1) 30 (8.6)
Anxiety/depression 1 323 (68.6) 192 (73.6) 132 (80.5) 254 (73.0) 0.05
2 137 (29.1) 60 (23.0) 29 (17.7) 89 (25.6)
3 11 (2.3) 9 (3.4) 3 (1.8) 5 (1.4)

Values are presented as number (%).

a

EQ-5D is divided into three levels (1: no, 2: some, and 3: extreme) of perceived problems.

b

p-values of chi-square test.

Table 3.

Odds ratios and 95% confidence interval for impaired health-related quality of life

Thermoelectric power plant Steel mill Petrochemical industry
Sex Male 1.00 (reference) 1.00 (reference) 1.00 (reference)
Female 2.76 (1.40, 5.43) 10.99 (2.12, 57.03) 5.26 (0.40, 68.25)
Age ≤59 1.00 (reference) 1.00 (reference) 1.00 (reference)
60-69 2.00 (0.78, 5.10) 7.26 (0.68, 77.45) 0.49 (0.03, 9.45)
≥70 4.91 (1.89, 12.79) 10.59 (0.89, 125.28) 2.78 (0.13, 60.47)
Marital status Yes 1.00 (reference) 1.00 (reference) 1.00 (reference)
Noa 0.59 (0.30, 1.18) 0.74 (0.25, 2.21) 1.01 (0.22, 4.75)
Monthly income (104 Korean won) ≤49 1.00 (reference) 1.00 (reference) 1.00 (reference)
50-199 0.75 (0.32, 1.77) 0.23 (0.02, 2.28) 1.24 (0.07, 21.00)
≥200 0.71 (0.30, 1.71) 0.99 (0.13, 7.77) 0.78 (0.03, 19.56)
Education Uneducated 1.00 (reference) 1.00 (reference) 1.00 (reference)
Elementary school 1.62 (0.74, 3.54) 1.13 (0.16, 7.81) 0.67 (0.06, 7.49)
top school or higher 1.28 (0.48, 3.47) 0.97 (0.11, 8.67) 1.71 (0.10, 29.43)
Employed status Yes 1.00 (reference) 1.00 (reference) 1.00 (reference)
No 0.80 (0.44, 1.46) 0.84 (0.27, 2.61) 0.36 (0.06, 1.97)
Chronic diseaseb Yes 1.00 (reference) 1.00 (reference) 1.00 (reference)
No 0.95 (0.55, 1.63) 1.72 (0.61, 4.81) 2.50 (0.53, 11.75)

Values are presented as odds ratio (95% confidence interval).

The lowest 10% level in Euro quality of life-5 dimension score of control group was cut-off values for determining impaired health-related quality of life.

a

Unmarried/divorced/widowed.

b

Hypertension, diabetes mellitus, dyslipidemia, chronic obstructive pulmonary disease.

Table 4.

Means and standard deviations of Euro quality of life-5 dimension according to the distance of industrial facilities

n Thermoelectric power plant n Steel mill n Petrochemical industry Groupa
Distance (km) ≤999 130 0.84±0.12 109 0.85±0.10 12 0.85±0.11 A, B
1000-2999 254 0.82±0.13 129 0.83±0.15 91 0.83±0.12 B
≥3000 79 0.81±0.14 23 0.86±0.09 60 0.88±0.11 A
p-valueb 0.09 0.40 0.02

Values are presented as mean±standard deviation.

a

The group is divided by post-hoc Tukey test.

b

p-values of one-way analysis of variance.

Table 5.

Odds ratios and 95% confidence intervals for impaired health-related quality of life according to living region

Crude Adjusteda
Control 1.00 (reference) 1.00 (reference)
Industrial areasb 1.32 (0.87, 2.00) 1.19 (0.77, 1.83)
Thermoelectric power plant 1.78 (1.14, 2.77) 1.59 (1.00, 2.53)
Steel mill 0.99 (0.57, 1.73) 0.94 (0.53, 1.69)
Petrochemical industry 0.64 (0.31, 1.33) 0.54 (0.25, 1.16)

Values are presented as odds ratio (95% confidence interval).

The lowest 10% level in Euro quality of life-5 dimension score of control group was cut-off values for determining impaired health-related quality of life.

a

Adjusted for sex, age, marital status, monthly income, education, employed status, chronic disease.

b

Industrial areas were included thermoelectric power plant, steel mill, petrochemical industry.