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Journal of Environmental Toxicology 2010;25(1):1-10.
잠재적 생체지표 발굴을 위한 토양선충 Caenorhabditis elegans에서의 유전자 발현 연구
노지연, 최진희
1서울시립대학교 환경공학과
2서울시립대학교 환경공학과
Gene Expression Profiling in the Nematode Caenorhabditis elegans, as a Potential Biomarker for Soil Ecotoxicology
Ji-Yeon Roh , Jinhee Choi
1
2
ABSTRACT
  Monitoring toxicity levels in specific biological compartments is necessary to evaluate the ecotoxicological risk associated with soil environmental pollution. Gene expression, as potential biomarker, is increasingly used as rapid early warning systems in environmental monitoring and ecological risk assessment procedures. Various representative species are currently used for the purpose of assessing soil toxicity, however, investigations on toxicological assessments using endpoint based on gene-level have been limited. In this review, we will present the current trends in organisms and endpoints used in soil toxicity study and report gene expression related to toxicity using soil organism, and C. elegans as promising organisms for this approach.
Keywords: gene expression profiling; Caenorhabditis elegans; soil ecotixicology
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