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Journal of Environmental Toxicology 2007;22(1):27-36.
국내 개발된 N-tox<SUP>®</SUP> 생물검정 시스템을 이용한 시안과 3, 5-이염화페놀의 발광박테리아 (Vibrio fischeri)에 대한 혼합 독성 영향 연구
이정석, 이규태, 김찬국, 김혜진, 이창훈, 이종현
Toxicity of Binary Mixture of Cyanide and 3, 5-dichlorophenol to Vibrio fischeri Determined by Newly Developed N-tox<SUP>®</SUP> Bioassay System
Jung-Suk Lee , Kyu-Tae Lee , Chan-Kook Kim , Hye-Jin Kim , Chang-Hoon Lee , Jong-Hyeon Lee
  Cyanides and dichlorophenols were important pollutants in industrial effluents of steel, petroleum, plastics, pesticides, synthetic dye and/or fiber manufacturing. The toxic effects of cyanide and 3, 5-dichlorophenol in the unary and binary solutions to Vibrio fischeri were determined using the newly developed N-tox<SUP>®</SUP> bioassay system. This bioassay system relies upon the attenuation of light intensity emitted by Vibrio fischeri exposed to various pollutants including metals and organic compounds. Most of studies dealing with toxicity of pollutants concerned single chemical species, while the organisms were typically exposed to pollutant mixtures. The present study showed that the toxicity of some binary combinations of cyanide and 3, 5-dichlorophenol significantly was lower than the predicted toxicity from the additive model. This antagonistic interaction was well explained by chemical interaction model presented in this study.
Keywords: Vibrio fischeri; bioassay; toxicity of pollutant mixture
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