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Journal of Environmental Toxicology 2006;21(4):317-322.
1, 2, 4-trimethylbenzene의 미생물복귀돌연변이시험
김수진, 조해원, 임경택, 맹승희, 김현영
Bacterial Reverse Mutation Test of 1, 2, 4-trimethylbenzene
Soo Jin Kim , Hae Won Cho , Kyung Taek Rim , Seung Hee Maeng , Hyeon Yeong Kim
ABSTRACT
  We have investigated the genotoxicity of 1, 2, 4-trimethylbenzene using Ames reverse mutation test. In Ames reverse mutation test, 1, 2, 4-trimethylbenzene treatment at the dose of 100, 50, 25, 12.5, 6.25 ㎍/plate did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA 1537 and in Escherichia coli WP2uvrA with and without metabolic activation. These results indicate that 1, 2, 4-trimethylbenzene has no mutagenic potential under the condition in this study.
Keywords: reverse mutation; 1, 2, 4-trimethylbenzene
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