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Journal of Environmental Toxicology 2004;19(4):383-388.
한국인 간장 및 신장피질에 함유된 카드뮴, 구리, 수은, 아연 함량과 메탈로치오나인과의 관계
이상기, 유영찬, 윤여표, 양자열, 오승민, 정규혁
Relationships Between Cadmium, Copper, Mercury, Zinc Levels and Metallothionein in the Liver and Kidney Cortex of Korean
Sang Ki Lee , Young Chan Yoo , Yeo Pyo Yun , Ja Youl Yang , Seung Min Oh , Kyu Hyuck Chung
ABSTRACT
In order to elucidate the relationships between cadmium, copper, mercury, zinc levels and metallothionein in the liver and kidney cortex of Korean, the levels of Cd, Zn, Hg, Cu and metallothionein (MT) were determined in the kidney cortex and liver of 50 subjects deceased in the period of January-November, 2001 in the area of seoul and Gyeonggi Province of Korea The mean age of the population studied was 36.3+/-12.3 years The tissues were digested with microwave digestion system and the elements were determined by inductively coupled plasma atomic emission spectiometry MT Was determined by the Cd-hemoglobin affinity assay The determined levels (mean+/-SD) were 33.9+/-18.9 micrograms Cd/g wet weight, 47.5+/12.6 micro-grams Zn/g wet weight, 2.5+/0.57 microgram Cu/g wet weight, 0.26+/-0.31 miciograms Hg/g wet weight 4.0+/3.1 mg MT/g wet weight in renal cortex and 2.5+/1.9 micrograms Cd/g wet weight 46.9+/-15.0 micrograms Zn/g wet weight, 6.2+/-2.5 micrograms Cu/g wet weight, 0.10+/-0.15 microgiams Hg/g wet weight, 0.92+/-0.57 mg MT/g wet weight in the liver Positive relationships between Cd and MT, sum of four divalent metal and MT in the kidney cortex were observed No other corielation was found between Cu and MT, Hg and MT, Zn and MT in either organs
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Reference Value of Mercury in Liver and Kidney of Korean  2002 June;17(2)
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