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Journal of Environmental Toxicology 2004;19(2):153-159.
염모제 도포방법에 따른 인체 적혈구의 산화스트레스 비교
김영철, 심미자, 권정숙
Comparison of Oxidative Stress in Red Blood Cells Induced by Hair Dyeing Application to Young Women
Young-Chul Kim , Mi-Ja Sim , Chong-Suk Kwon
ABSTRACT
To ascertain the effects of hair dyeing application on oxidative stress in human, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp (conventional dyeing) and a hair dyeing with 3 to 4 mm away from the scalp (alternative dyeing) were applied to each 15 young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours after the hair dyeing. and antioxidant enzyme activities and antioxidant contents were measured in red blood cells. After dyeing. malondialdehyde (MDA) contents for conventional dyeing group was shown to a tendence of more increased than alternative dyeing group. After dyeing, reduced glutathione (GSH) contents for conventional dyeing group was shown to a tendence of more decreased than alternative dyeing group. After dyeing, superoxide dismutase (SOD) and catalase (CAT) activities were significantly decreased in conventional dyeing group (p<0.01), however, SOD and CAT activities were not significantly decreased in alternative dyeing group. After dyeing, there was no significant decrease in glutathione peroxidase (GPX) activity both for conventional dyeing group and alternative dyeing group. Therefore, after dyeing, the degree of oxidative stress in red blood cells for alternative dyeing group was appeared to he lower than conventional dyeing group.
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